Synthetic Biology

• Corporate Author: SpringerLink (Online service)
• Other Authors: Glieder, Anton (Editor), Kubicek, Christian P. (Editor), Mattanovich, Diethard (Editor), Wiltschi, Birgit (Editor), Sauer, Michael (Editor)
• Format: Electronic eBook
• Language: English
• Published: Cham : Springer International Publishing : Imprint: Springer, 2016.
• Edition: 1st ed. 2016.
• Subjects: Life sciences.; Biochemical engineering.; Genetic engineering.; Systems biology.; Biomaterials.; Life Sciences.; Systems Biology.; Biochemical Engineering.; Genetic Engineering.

The emerging field of synthetic biology employs biotechnological approaches to recreate and enhance basic biological structures, intracellular processes and whole organisms. This book provides a comprehensive, up-to-date overview of the opportunities and challenges of this complex field of biotechno...

Table of Contents:

• Xenobiotic life (artificial cells and cell like structures, biological nanostructures, XNA)
• Novel DNA and RNA (synthetic promoters, riboswitches, small RNAs, ribozymes, adaptamers, DNA walker, DNA machines)
• Expansion of the genetic code and protein building blocks (orthogonal mRNA-ribosome pairs, non canonical amino acids)
• DNA logics and circuit design (including sensors, TALORs, genome rewiring repressilator, oscillator, metabolator, „Multicellular circuits“)
• Protein engineering (directed evolution, domain engineering)
• Synthetic metabolic pathways (engineered pathways, non natural pathways, scaffolding)
• Reengineered chassis cells (minimal organisms, platform hosts, minimal genomes, synthetic genomes)
• In silico simulation and design of complex metabolic and signalling networks
• Novel synthetic biomaterials
• Key methods for synthetic biology (assembly technologies, genome engineering technologies, DNA synthesis, Standardization)
• Public awareness and risk management.