Agammaglobulinemia

• Corporate Author: SpringerLink (Online service)
• Other Authors: Plebani, Alessandro (Editor), Lougaris, Vassilios (Editor)
• Format: Electronic eBook
• Language: English
• Published: Cham : Springer International Publishing : Imprint: Springer, 2015.
• Edition: 1st ed. 2015.
• Series: Rare Diseases of the Immune System, 4
• Subjects: Medicine.; Immunology.; Hematology.; Rheumatology.; Pediatrics.; Cell biology.; Biomedicine.; Cell Biology.

This book provides an updated overview of agammaglobulinemia, a rare form of primary immunodeficiency which is considered the prototype of the congenital humoral defects, and which is characterized by the absence of peripheral B cells and very low serum immunoglobulin levels. The book opens by discu...

Table of Contents:

• Early B Cell Biology
• Agammaglobulinemia: Basic Pathogenesis and Clinical Spectrum (Including X-Linked and Autosomal Recessive Forms)
• Pulmonary Complications in Agammaglobulinemia
• Immunoglobulin Replacement Therapy: Past, Present, Future
• Mutational Spectrum of BTK: A Comprehensive Description
• Novel Therapeutic Options for X-Linked Agammaglobulinemia
• BTK in Non B Cells.