Understanding Kidney Diseases

• Κύριοι συγγραφείς: Rayner, Hugh C. (Συγγραφέας), Thomas, Mark (Συγγραφέας), Milford, David (Συγγραφέας)
• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Cham : Springer International Publishing : Imprint: Springer, 2016.
• Θέματα: Medicine.; Diabetes.; Nephrology.; Medicine & Public Health.

This book provides the essential understanding needed for the assessment of patients with kidney disease. The chapters follow the sequence taken during a clinic consultation and when clerking a patient. At each stage, the principles and concepts underlying aspects of renal medicine that may seem dif...

Πίνακας περιεχομένων:

• Introduction
• The purpose of the book – understanding the natural history of kidney disease
• how displaying a GFR history is a fundamental part of the clinical assessment of kidney diseases
• how the eGFR graph is used to inform patients and plan treatment.-principles but not details of treatment
• The basics of creatinine measurement and eGFR equations in adults
• Simple guide to the classification of AKI, AKD and CKD
• Stages of CKD – including proteinuria
• The meaning of ‘stability’ in an eGFR graph – variation over time
• Cases
• Section 1: Acute kidney injury – changes over 50% drop, assuming no asymmetry)
• Recurrent AKI leading to CKD
• Section 2: AKD – changes >48 hours 3months
• Patterns of progression – Linear and Non-linear
• Monitoring response to treatment – e.g. immunosuppression for GN, BP control in malignant hypertension
• Section 4: CKD – changes over years
• non-progressive (stable) CKD  - e.g. obstructive uropathy
• progressive CKD – e.g. transplant nephropathy, lithium nephrotoxicity, role of proteinuria as risk marker
• Use of graphs to plan future renal replacement therapy – e.g. linear progression in ADPKD
• Section 5: Acute-on-chronic kidney disease
• Chronic slowly progressive diabetic nephropathy with superimposed acute pathology, e.g. response to ACEI/ARB, contrast nephropathy, glomerulonephritis, interstitial nephritis
• Transplant rejection
• Pregnancy in women with CKD
• Section 6: Nephrotic syndrome
• GFR, serum albumin and urinary PCR graphs – use to monitor treatment and relapses, and to plan treatment
• Section 7: Other graphs
• 24 hour BP measurement – importance of nocturnal dip and timing of antihypertensives in CKD care
• Diabetes mellitus - HbA1c – colour coding as patient education tool; role of glucose control in preventing diabetic nephropathy (but no impact once CKD established)
• Serum free light chains and myeloma kidney/light chain nephropathy/immune GN
• Conclusions
• eGFR graphs – an essential tool in patient assessment which tells the story of kidney disease
• The role of graphs (eGFR, 24 hour BP, and HbA1c) in patient education and support of self-management
• Role of eGFR graphs in systematic CKD surveillance by renal units and pathology labs – evidence of benefit.