ABC Transporters - 40 Years on

• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Άλλοι συγγραφείς: George, Anthony M. (Επιμελητής έκδοσης)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Cham : Springer International Publishing : Imprint: Springer, 2016.
• Θέματα: Life sciences.; Drug resistance.; Biochemistry.; Cell membranes.; Life Sciences.; Membrane Biology.; Biological and Medical Physics, Biophysics.; Biochemistry, general.; Drug Resistance.

This book provides new structural, biochemical, and clinical information on ABC transporters. The authors explore and describe the state of the art of research, knowledge, and prospects for the future for this important family of proteins. The first ABC transporter was discovered in 1973 and was nam...

Πίνακας περιεχομένων:

• ABC Importers
• Inborn errors and potential correction of the cellular expression and localization of medically important ABC transporters
• Human ABC transporter ABCC11: Molecular mechanistic, pharmacological, and anthropological aspects
• Biology of mitochondrial ABCs and their contribution to pathology
• ABC transporters and multidrug resistance in fungi and yeast
• Structural and mechanistic insights into modulation of P-glycoprotein (ABCB1)function by tyrosine kinase inhibitors
• Techniques for the purification of ABC transporters
• HDAC inhibitors and MDR ABC transporters
• The role of polymorphisms in P-glycoprotein (ABCB1) on function
• Interaction of ABC transporters with drugs
• ABC insights from CFTR.