Antimicrobial Peptides Role in Human Health and Disease /

This book focuses on the importance of human antimicrobial peptides (AMP) in keeping the host healthy and preventing infectious diseases. The first chapters deal with several examples of the role of AMP in different epithelial organs (skin and wound healing, eye, lung, genito-urinary tract, gut), wh...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
Άλλοι συγγραφείς: Harder, Jürgen (Επιμελητής έκδοσης), Schröder, Jens-M (Επιμελητής έκδοσης)
Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
Γλώσσα:English
Έκδοση: Cham : Springer International Publishing : Imprint: Springer, 2016.
Σειρά:Birkhäuser Advances in Infectious Diseases
Θέματα:
Διαθέσιμο Online:Full Text via HEAL-Link
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245 1 0 |a Antimicrobial Peptides  |h [electronic resource] :  |b Role in Human Health and Disease /  |c edited by Jürgen Harder, Jens-M. Schröder. 
264 1 |a Cham :  |b Springer International Publishing :  |b Imprint: Springer,  |c 2016. 
300 |a VI, 158 p. 10 illus. in color.  |b online resource. 
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490 1 |a Birkhäuser Advances in Infectious Diseases 
505 0 |a Antimicrobial peptides in cutaneous wound healing -- Antimicrobial peptides as endogenous antibacterials and antivirals at the ocular surface -- Function of antimicrobial peptides in lung innate immunity -- Role of antimicrobial peptides to prevent infections in the kidney and urinary tract -- Antimicrobial peptides in the gut -- Metal sequestration: An important contribution of antimicrobial peptides to nutritional immunity -- Regulation of antimicrobial peptide gene expression by vitamin D -- Dichotomous roles of cationic polypeptides targeting HIV -- Antimicrobial peptides in host-defense: functions beyond antimicrobial activity. 
520 |a This book focuses on the importance of human antimicrobial peptides (AMP) in keeping the host healthy and preventing infectious diseases. The first chapters deal with several examples of the role of AMP in different epithelial organs (skin and wound healing, eye, lung, genito-urinary tract, gut), which are exposed to different kinds of infectious microorganisms and as a result produce different patterns of AMP. Examples of the dysregulation of AMP expression and function promoting infections are discussed. The capacity of AMP to restrict the availability of essential metals to bacteria as an efficient antibacterial strategy in nutritional immunity is discussed in the next chapter. Our current understanding of how vitamin D, the sunshine vitamin, influences AMP-expression and how this can affect our health is also addressed. Last but not least, the role of AMP in HIV infection and the immunomodulatory properties of AMP highlight the diverse facets of AMP in host immunity. AMP’s specific functions, including in fighting multi-resistant bacteria, suggest that they may offer therapeutic benefits – a question that is discussed in the final chapter. 
650 0 |a Medicine. 
650 0 |a Immunology. 
650 0 |a Microbiology. 
650 1 4 |a Biomedicine. 
650 2 4 |a Immunology. 
650 2 4 |a Microbiology. 
700 1 |a Harder, Jürgen.  |e editor. 
700 1 |a Schröder, Jens-M.  |e editor. 
710 2 |a SpringerLink (Online service) 
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776 0 8 |i Printed edition:  |z 9783319241975 
830 0 |a Birkhäuser Advances in Infectious Diseases 
856 4 0 |u http://dx.doi.org/10.1007/978-3-319-24199-9  |z Full Text via HEAL-Link 
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950 |a Biomedical and Life Sciences (Springer-11642)