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|a 9783319249513
|9 978-3-319-24951-3
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|a 10.1007/978-3-319-24951-3
|2 doi
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|a RC261-271
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|a MED062000
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|a 614.5999
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|a Epigenetic Advancements in Cancer
|h [electronic resource] /
|c edited by Manoj K. Mishra, Kumar S. Bishnupuri.
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|a Cham :
|b Springer International Publishing :
|b Imprint: Springer,
|c 2016.
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|a XI, 246 p. 12 illus., 11 illus. in color.
|b online resource.
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|a text
|b txt
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|a 1. Role of DNA methylation in the progression and clearance of cancer -- 2. Epigenetical role for RNA in cancer progression -- 3. Epigenetics and its role in prostate cancer -- 4. Epigenetics and ovarian cancer -- 5. Epigenetics and breast cancer -- 6. Epigenetics and thyroid cancer -- 7. Epigenetics and intestinal cancer -- 8. Epigenetics and lung cancer -- 9. Epigenetics and renal cancer -- 10. Epigenetics and cervical cancer -- 11. Epigenetical markers in cancer -- 12. Epigenetical role in pancreatic cancer.
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|a This volume explores the epigenetic alterations and their association with various human cancers. Considering one of human cancer as an example, individual chapters are focused on defining the role of epigenetic regulators and underlying mechanisms in cancer growth and progression. Epigenetic alteration including DNA methylation, histone modification, nucleosome positioning and non-coding RNAs expression are involved in a complex network of regulating expression of oncogenes and tumor suppressor genes and constitute an important event of the multistep process of carcinogenesis. Recent advances in the understanding of the epigenetic regulation and detailed information of these epigenetic changes in various cancers provide new avenues of advancements in diagnostics, prognostics, and therapies of this highly fatal disease.
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|a Medicine.
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|a Cancer research.
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|a Gene expression.
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|a Biomedicine.
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|a Cancer Research.
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| 650 |
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|a Gene Expression.
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| 700 |
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|a Mishra, Manoj K.
|e editor.
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| 700 |
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|a Bishnupuri, Kumar S.
|e editor.
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| 710 |
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|a SpringerLink (Online service)
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|t Springer eBooks
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|i Printed edition:
|z 9783319249490
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|u http://dx.doi.org/10.1007/978-3-319-24951-3
|z Full Text via HEAL-Link
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|a ZDB-2-SBL
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| 950 |
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|a Biomedical and Life Sciences (Springer-11642)
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