Pediatric Continuous Renal Replacement Therapy Principles and Practice /

• Main Authors: Assadi, Farahnak (Author), Ghane Sharbaf, Fatemeh (Author)
• Corporate Author: SpringerLink (Online service)
• Format: Electronic eBook
• Language: English
• Published: Cham : Springer International Publishing : Imprint: Springer, 2016.
• Edition: 1st ed. 2016.
• Subjects: Medicine.; Nephrology.; Pediatrics.; Medicine & Public Health.

This book provides a current understanding of Continuous Renal Replacement Therapies (CRRT) techniques with a focus on drug dosing in critically ill children receiving CRRT. Strategies include the role of therapeutic drug monitoring, effect of CRRT on drug pharmacokinetics, variations in the drugs p...

Table of Contents:

• Acute kidney injury
• CRRT as treatment
• Water and solute movements: basic physiology
• CRRT modalities
• Hemodialysis (diffusive) versus hemofiltraion (Convective) CVVH
• CRRT Principles
• General consideration for CRRT
• Specific consideration for pediatric CRRT
• Vascular access and catheter size
• Blood flow rate (BFR)
• Ultrafiltation rates
• Calculating the desired fluid removal rate
• Replacement/dialysate solutions
• Drug dosing in CRRT
• Blood priming
• Nutrition in CRRT
• Monitoring during CRRT
• Compliance of CRRT
• Replacement/dialysate solution composition
• Factors influencing the clearance of drug during CRRT
• CRRT impact on pharmacokinetic parameters
• Case Studies.-.