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03146nam a22004815i 4500 |
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978-3-319-26811-8 |
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20170517235455.0 |
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|a 9783319268118
|9 978-3-319-26811-8
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|a 10.1007/978-3-319-26811-8
|2 doi
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|a Parimelazhagan, Thangaraj.
|e author.
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|a Pharmacological Assays of Plant-Based Natural Products
|h [electronic resource] /
|c by Thangaraj Parimelazhagan.
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|a Cham :
|b Springer International Publishing :
|b Imprint: Springer,
|c 2016.
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|a XV, 188 p.
|b online resource.
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|a text
|b txt
|2 rdacontent
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|a computer
|b c
|2 rdamedia
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|a online resource
|b cr
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|a text file
|b PDF
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|a Progress in Drug Research,
|x 0071-786X ;
|v 71
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|a 1. Extraction of plant material -- 2. Critical aspects of purification and impurities in natural product extracts. 3. In vitro antioxidant assays -- 4. In vivo antioxidant assays -- 5. Quantification assays -- 6. Anti-nutritional factors -- 7. Anti-inflammatory activity -- 8. Antipyretic activity -- 9. Inflammation bowel disease -- 10. Anti-arthritic activity -- 11. Evaluation of analgesic potential -- 12. Anti-diarrhoeal activity -- 13. Anti-ulcer activity -- 14. In vitro anti-diabetic activity -- 15. In vivo anti-diabetic activity -- 16. Hepatoprotective property -- 17. Antitumor activity -- 18. In vivo wound healing studies -- 19. Determination of cytotoxicity -- 20. Evaluation of bioavailability -- 21. Molecular identification by DNA barcoding -- 22. Molecular docking of bioactive compounds against BRCA and COX proteins. .
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|a This volume provides information on how to select and screen plants for their medicinal properties. It describes phytopharmacological techniques for extracting and qualitatively and quantitatively analyzing a plant’s phytochemicals. After a detailed in vitro investigation including nutritional and anti-nutritional analyses, medicinal properties were tested with various in vivo models for anti-inflammatory, analgesic, anti-pyretic, anticancer and anti-diabetic properties, as well as wound healing, neurodegenerative diseases, etc. Compound identification and purification techniques include, among others, TLC and column chromatography, as well as molecular docking with specific proteins.
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|a Medicine.
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|a Pharmacology.
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| 650 |
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|a Analytical chemistry.
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| 650 |
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|a Plant biochemistry.
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|a Biomedicine.
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|a Pharmacology/Toxicology.
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| 650 |
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|a Plant Biochemistry.
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| 650 |
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|a Analytical Chemistry.
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| 710 |
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|a SpringerLink (Online service)
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|t Springer eBooks
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8 |
|i Printed edition:
|z 9783319268101
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| 830 |
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|a Progress in Drug Research,
|x 0071-786X ;
|v 71
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| 856 |
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|u http://dx.doi.org/10.1007/978-3-319-26811-8
|z Full Text via HEAL-Link
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| 912 |
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|a ZDB-2-SBL
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| 950 |
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|a Biomedical and Life Sciences (Springer-11642)
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