Myeloid-Derived Suppressor Cells and Cancer

• Κύριοι συγγραφείς: Escors, David (Συγγραφέας), Talmadge, James E. (Συγγραφέας), Breckpot, Karine (Συγγραφέας), Van Ginderachter, Jo A. (Συγγραφέας), Kochan, Grazyna (Συγγραφέας)
• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Cham : Springer International Publishing : Imprint: Springer, 2016.
• Έκδοση: 1st ed. 2016.
• Σειρά: SpringerBriefs in Immunology,
• Θέματα: Medicine.; Cancer research.; Immunology.; Oncology.; Cell biology.; Biomedicine.; Cancer Research.; Cell Biology.

The book starts with an introduction to and history of myeloid-derived suppressor cells (MDSCs), followed by a description of their differentiation, their role in the tumour microenvironment and their therapeutic targeting. It closes with an outlook on future developments. In cancer patients, myelop...

Πίνακας περιεχομένων:

• Controversies in Neoplastic Myeloplasia
• Differentiation of Murine Myeloid-derived Suppressor Cells
• Human MDSCs
• Ex Vivo MDSC Differentiation Models
• Immunoregulatory myeloid cells in the tumor microenvironment
• Signal Transducer and Activation of Transcription 3: A Master Regulator of Myeloid-derived Suppressor Cells
• Future Perspectives.