Clinical Pharmacology: Current Topics and Case Studies

• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Άλλοι συγγραφείς: Müller, Markus (Επιμελητής έκδοσης)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Cham : Springer International Publishing : Imprint: Springer, 2016.
• Έκδοση: 2nd ed. 2016.
• Θέματα: Medicine.; Pharmacy.; Pharmacology.; Pharmacotherapy.; Biomedicine.; Pharmacology/Toxicology.

This revised and extended second edition focuses on current and emerging topics in drug development, their molecular mechanisms of action as well as regulatory issues. In addition, in-depth insights into clinical drug research and trial methodology are presented on the basis of concrete case studies...

Πίνακας περιεχομένων:

• The discipline of Clinical Pharmacology
• Current issues in drug development
• Current issues in drug regulation
• Current issues in drug reimbursement
• Ethics of clinical research
• GCP, Scientific misconduct
• Phases of drug development, first in man studies
• Clinical trials - Interventional studies
• Clinical trials - observational studies
• Imaging
• Microdosing
• Genomics
• Pharmacokinetics/Pharmacodynamics
• Epidemiology, statistics
• Placebo effects
• Pharmaceutical drug safety
• Drug interactions
• Advanced therapies
• Biological pharmaceuticals
• Generic drugs, Enantiomers
• Special situations I: orphan drugs
• Special situations II: sex differences
• Special situations III: children.