Translational Toxicology Defining a New Therapeutic Discipline /

• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Άλλοι συγγραφείς: Hughes, Claude L. (Επιμελητής έκδοσης), Waters, Michael D. (Επιμελητής έκδοσης)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Cham : Springer International Publishing : Imprint: Humana Press, 2016.
• Έκδοση: 1st ed. 2016.
• Σειρά: Molecular and Integrative Toxicology,
• Θέματα: Medicine.; Pharmacology.; Environmental health.; Biomedicine.; Pharmacology/Toxicology.; Environmental Health.

Bringing together a distinguished interdisciplinary team of contributors, this volume provides a comprehensive exploration of translational toxicology—a systematic approach to developing therapeutic interventions that can protect against, mitigate, or reverse the effects of exposures. In particular,...

Πίνακας περιεχομένων:

• I.Introduction
• The Opportunity to Translate Developmental Toxicology into a Therapeutic Discipline
• The Role of Toxicokinetics and Toxicodynamics in Developmental and Translational Toxicology
• II.Toxicant Modes of Action and Biomarkers
• Mutational Effects
• Ligand-Mediated Toxicology: Characterization and Translational Prospects
• Effects of Environmentally Acquired Heavy Metals and Nutrients on the Epigenome and Phenotype
• Fetal Imaging and Effects of Exposures on Growth and Function
• III.Developmental Risks of Exposures and Potential Translational Toxicology Therapeutics
• Ovarian Toxicity of Environmental Contaminants: 50 Shades of Grey
• The “Toxic” Effects of a Perinatal Obesogenic Environment: Maternal Obesity and Impacts on Future Generations
• The Role of Environmental Exposures in Preterm Birth
• The Impact of Environmental Stressors on DNA Methylation, Neurobehavioral Development and Chronic Physical Aggression: Prospects for Early Protective Interventions
• Coffee Health Effects from Early Fetal Development through Childhood and Adolescence.