Modeling in Biopharmaceutics, Pharmacokinetics and Pharmacodynamics Homogeneous and Heterogeneous Approaches /

• Main Authors: Macheras, Panos (Author), Iliadis, Athanassios (Author)
• Corporate Author: SpringerLink (Online service)
• Format: Electronic eBook
• Language: English
• Published: Cham : Springer International Publishing : Imprint: Springer, 2016.
• Edition: 2nd ed. 2016.
• Series: Interdisciplinary Applied Mathematics, 30
• Subjects: Mathematics.; Pharmacology.; Biochemistry.; Applied mathematics.; Engineering mathematics.; Biomathematics.; Biophysics.; Biological physics.; Biomedical engineering.; Mathematical and Computational Biology.; Pharmacology/Toxicology.; Biophysics and Biological Physics.; Biomedical Engineering.; Biochemistry, general.; Applications of Mathematics.

The state of the art in Biopharmaceutics, Pharmacokinetics, and Pharmacodynamics Modeling is presented in this new second edition book. It shows how advanced physical and mathematical methods can expand classical models in order to cover heterogeneous drug-biological processes and therapeutic effect...

Table of Contents:

• Part I: Basic Concepts
• The Geometry of Nature
• Diffusion and Kinetics
• Nonlinear Dynamics
• Part II: Modeling in Biopharmaceutics
• Drug Release
• Drug Dissolution
• Oral Drug Absorption
• Part III: Modeling in Pharmacokinetics
• Empirical Models
• Deterministic Compartmental Models
• Fractional Pharmacokinetics
• Modeling and Simulation in Bioequivalence
• Stochastic Compartmental Models
• Part IV: Modeling in Pharmacodynamics
• Classical Pharmacodynamics
• Nonclassical Pharmacodynamics
• Appendices.