Lipoxygenases in Inflammation

• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Άλλοι συγγραφείς: Steinhilber, Dieter (Επιμελητής έκδοσης)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Cham : Springer International Publishing : Imprint: Springer, 2016.
• Σειρά: Progress in Inflammation Research
• Θέματα: Medicine.; Human physiology.; Immunology.; Enzymology.; Lipids.; Biomedicine.; Lipidology.; Human Physiology.

Oxidation of polyunsaturated fatty acids by lipoxygenases leads to a variety of fatty acid metabolites which play important roles in physiology but also in pathophysiology. Data accumulated during the last decade point to the fact that lipoxygenase metabolites are involved in host defence reactions,...

Πίνακας περιεχομένων:

• Introduction into lipoxygenases
• 5-Lipoxygenase
• Leukotriene A4 hydrolase and LTC4 synthase
• Catalytic multiplicity of 15-lipoxygenase-1 orthologs (ALOX15) of different species
• Platelets and lipoxygenases
• Lipoxygenases and cardiovascular diseases
• Role of lipoxygenases in pathogenesis of cancer
• The physiology and pathophysiology of lipoxygenases in the skin
• 5-Oxo-ETE and inflammation
• Lipoxins, resolvins, and the resolution of inflammation.