The Role of Microenvironment in the Control of Tumor Angiogenesis

• Main Author: Ribatti, Domenico (Author)
• Corporate Author: SpringerLink (Online service)
• Format: Electronic eBook
• Language: English
• Published: Cham : Springer International Publishing : Imprint: Springer, 2016.
• Edition: 1st ed. 2016.
• Subjects: Medicine.; Cancer research.; Oncology.; Pathology.; Pharmacotherapy.; Biomedicine.; Cancer Research.

This work describes the importance of tumor microenvironment in favouring tumor progression and angiogenesis. Under physiological conditions, angiogenesis is dependent on the balance of positive and negative angiogenic modulators within the vascular microenvironment and requires the functional activ...

Table of Contents:

• Prelims
• Tumor microenvironment
• Tumor blood vessels and tumor endothelial cells
• Tumor angiogenesis
• Inflammatory cells in tumor microenvironment
• Therapeutic strategies, the concept of “normalization” and the role of VEGF inhibition
• Index. .