Mitochondrial Dysfunction in Neurodegenerative Disorders

This second edition brings together up-to-date contributions from leaders in the field internationally on the various ways in which mitochondrial dysfunction contributes to the pathogenesis of neurodegenerative diseases, including Parkinson’s disease, Alzheimer’s disease and multiple sclerosis. The...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
Άλλοι συγγραφείς: Reeve, Amy K. (Επιμελητής έκδοσης), Simcox, Eve M. (Επιμελητής έκδοσης), Duchen, Michael R. (Επιμελητής έκδοσης), Turnbull, Doug M. (Επιμελητής έκδοσης)
Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
Γλώσσα:English
Έκδοση: Cham : Springer International Publishing : Imprint: Springer, 2016.
Έκδοση:2nd ed. 2016.
Θέματα:
Διαθέσιμο Online:Full Text via HEAL-Link
Πίνακας περιεχομένων:
  • Part I. Mitochondria and Neurodegenerative Disease
  • An Introduction to Mitochondria, Their Structure and Functions
  • Part II. Mitochondrial Dysfunction: Causes and Effects?
  • Neurodegeneration in Mitochondrial Disorders
  • The Ageing Brain, Mitochondria and Neurodegeneration
  • Mitochondrial Genes and Neurodegenerative Disease
  • Mitochondrial Signalling and Neurodegeneration
  • Part III. Functional Consequences of Mitochondrial Dysfunction
  • Life on the Edge: Determinants of Selective Neuronal Vulnerability in Parkinson’s Disease
  • Mitochondrial Dynamics and Neurodegeneration
  • Mitochondrial Dysfunction and Transport in Demyelinating Disease with Inflammation
  • Mitochondria, the Synapse, and Neurodegeneration
  • Protein Misfolding and Aggregation: Implications for Mitochondrial Dysfunction and Neurodegeneration
  • Mitochondrial Degradation, Autophagy and Neurodegenerative Disease
  • The Deleterious Duo of Neurodegeneration: Lysosomes and Mitochondria
  • Part IV. Measuring the Contribution of Mitochondrial Dysfunction to Neurodegenerative Disease
  • Can We Accurately Model Mitochondrial Dysfunction in Neurodegeneration?
  • Mitochondrial Function and Dynamics Imaged In Vivo
  • Part V. The Future
  • Development of Treatments and Therapies to Target Mitochondrial Dysfunction
  • Summary and Conclusions.