RNA Processing Disease and Genome-wide Probing /

Ribonucleic acid (RNA) binding proteins currently number in the thousands and defects in their function are at the heart of diseases such as cancer and neurodegeneration. RNA binding proteins have become implicated in the intricate control of surprisingly diverse biological settings, such as circadi...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
Άλλοι συγγραφείς: Yeo, Gene W. (Επιμελητής έκδοσης)
Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
Γλώσσα:English
Έκδοση: Cham : Springer International Publishing : Imprint: Springer, 2016.
Σειρά:Advances in Experimental Medicine and Biology, 907
Θέματα:
Διαθέσιμο Online:Full Text via HEAL-Link
LEADER 03048nam a22004575i 4500
001 978-3-319-29073-7
003 DE-He213
005 20160602181608.0
007 cr nn 008mamaa
008 160602s2016 gw | s |||| 0|eng d
020 |a 9783319290737  |9 978-3-319-29073-7 
024 7 |a 10.1007/978-3-319-29073-7  |2 doi 
040 |d GrThAP 
050 4 |a RB155-155.8 
050 4 |a QH431 
072 7 |a MFN  |2 bicssc 
072 7 |a MED107000  |2 bisacsh 
082 0 4 |a 611.01816  |2 23 
082 0 4 |a 599.935  |2 23 
245 1 0 |a RNA Processing  |h [electronic resource] :  |b Disease and Genome-wide Probing /  |c edited by Gene W. Yeo. 
264 1 |a Cham :  |b Springer International Publishing :  |b Imprint: Springer,  |c 2016. 
300 |a XIII, 326 p. 37 illus., 34 illus. in color.  |b online resource. 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
347 |a text file  |b PDF  |2 rda 
490 1 |a Advances in Experimental Medicine and Biology,  |x 0065-2598 ;  |v 907 
505 0 |a Experimental and computational considerations in the study of RNA binding protein-RNA interactions -- Genome-wide approaches for RNA structure probing -- Tethered function assays as tools to elucidate the molecular roles of RNA binding proteins -- Single molecule approaches in RNA-protein interactions -- RNA dynamics in the control of circadian rhythm -- Roles of RNA binding proteins and post-transcriptional regulation in driving male germ cell development in the mouse -- Regulation of stem cell self‐renewal and oncogenesis by RNA binding proteins -- Controlling the editor: the many roles of RNA binding proteins in regulating A-to-I RNA editing -- Mutations in splicing factors and cancer -- Regulation of tissue-specific alternative splicing: C. elegans as a model system -- RNA Granules and Diseases—A Case Study of Stress Granules in ALS and FTLD -- Post-translational modifications and RNA-binding proteins. 
520 |a Ribonucleic acid (RNA) binding proteins currently number in the thousands and defects in their function are at the heart of diseases such as cancer and neurodegeneration. RNA binding proteins have become implicated in the intricate control of surprisingly diverse biological settings, such as circadian rhythm, stem cell self-renewal, oncogenesis and germ cell development. This book surveys a range of genome-wide and systems approaches to studying RNA binding proteins, the importance of RNA binding proteins in development, cancer and circadian rhythm. . 
650 0 |a Medicine. 
650 0 |a Human genetics. 
650 1 4 |a Biomedicine. 
650 2 4 |a Human Genetics. 
700 1 |a Yeo, Gene W.  |e editor. 
710 2 |a SpringerLink (Online service) 
773 0 |t Springer eBooks 
776 0 8 |i Printed edition:  |z 9783319290713 
830 0 |a Advances in Experimental Medicine and Biology,  |x 0065-2598 ;  |v 907 
856 4 0 |u http://dx.doi.org/10.1007/978-3-319-29073-7  |z Full Text via HEAL-Link 
912 |a ZDB-2-SBL 
950 |a Biomedical and Life Sciences (Springer-11642)