Novel Immunotherapeutic Approaches to the Treatment of Cancer Drug Development and Clinical Application /

Cancer care is undergoing a radical transformation as novel technologies are directed toward new treatments and personalized medicine. The most dramatic advances in the treatment of cancer have come from therapeutics that augment the immune response to tumors. The immune checkpoint inhibitors are th...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
Άλλοι συγγραφείς: Rennert, Paul D. (Επιμελητής έκδοσης)
Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
Γλώσσα:English
Έκδοση: Cham : Springer International Publishing : Imprint: Springer, 2016.
Θέματα:
Διαθέσιμο Online:Full Text via HEAL-Link
Πίνακας περιεχομένων:
  • Introduction
  • Enhancing the efficacy of checkpoint blockade through combination therapies
  • Novel Immunomodulatory Targets in the Immunoglobulin-Superfamily
  • Parallel Costimulation of Effector and Regulatory T Cells by OX40, GITR, TNFRSF25, CD27 and CD137
  • NK Cell Responses in Immunotherapy
  • Reversing T cell dysfunction for tumor immunotherapy
  • Immunomodulation within a single tumor site to induce systemic anti-tumor immunity
  • Novel Targets and Their Assessment for Cancer Treatment
  • The New Frontier of Antibody Drug Conjugates
  • Cellular Therapies
  • Targeting the Physicochemical, Cellular, and Immunosuppressive Properties of the Tumor Microenvironment by Depletion of Hyaluronan to Treat Cancer.