Autophagy Networks in Inflammation

• Corporate Author: SpringerLink (Online service)
• Other Authors: Maiuri, Maria Chiara (Editor), De Stefano, Daniela (Editor)
• Format: Electronic eBook
• Language: English
• Published: Cham : Springer International Publishing : Imprint: Springer, 2016.
• Series: Progress in Inflammation Research
• Subjects: Medicine.; Immunology.; Infectious diseases.; Cell biology.; Biomedicine.; Cell Biology.; Infectious Diseases.

Autophagy principally serves an adaptive function to protect organisms against diverse human pathologies, including cancer and neurodegeneration. Recent developments using in vitro, ex vivo and in vivo models show the involvement of the autophagy pathway in immunity and inflammation. Moreover, direc...

Table of Contents:

• Autophagy in direct pathogen elimination (Xenophagy)
• Autophagy and pattern recognition receptors
• Autophagy and inflammasomes
• Autophagy and Antigen presentation
• Autophagy and regulation of T and B cell function
• Autophagy in chronic inflammation
• The complex crosstalk between autophagy and ROS
• Lipophagy
• Autophagy, phagocytosis and entosis: who eats whom?- Which is the cell fate of inflammatory cells ? Autophagic cell death, pyroptosis, netosis, apoptosis, necrosis
• Host defence (virus/bacteria)
• Neurological diseases
• Pulmonary diseases (emphysema, COPD, etc.)
• Inflammatory bowel disease
• Target autophagy as a novel therapeutic strategy in autoimmune diseases
• Liver and pancreatic diseases
• Obesity
• Aging
• Overview on clinical trials.