Quantifying Interactions of Biomolecules with Inorganic Surfaces

• Main Author: Patra, Abhijeet (Author)
• Corporate Author: SpringerLink (Online service)
• Format: Electronic eBook
• Language: English
• Published: Cham : Springer International Publishing : Imprint: Springer, 2017.
• Series: Springer Theses, Recognizing Outstanding Ph.D. Research,
• Subjects: Physics.; Nanochemistry.; Amorphous substances.; Complex fluids.; Nanoscale science.; Nanoscience.; Nanostructures.; Physical measurements.; Measurement.; Materials > Surfaces.; Thin films.; Nanoscale Science and Technology.; Surfaces and Interfaces, Thin Films.; Soft and Granular Matter, Complex Fluids and Microfluidics.; Measurement Science and Instrumentation.
• Physical Description: XVIII, 102 p. 39 illus., 35 illus. in color. online resource.
• ISBN: 9783319307282
• ISSN: 2190-5053

This thesis demonstrates the adaptation of existing techniques and principles towards enabling clean and precise measurements of biomolecules interacting with inorganic surfaces. In particular, it includes real-time measurement of serum proteins interacting with engineered nanomaterial. Making meaningful and unambiguous measurements has been an evolving problem in the field of biology and its various allied domains, primarily due to the complex nature of experiments and the large number of possible interferants. The subsequent quantification of interactions between biomolecules and inorganic surfaces solves pressing problems in the rapidly developing fields of lipidomics and nanomedicine.