Heat Shock Protein Inhibitors Success Stories /

Medicinal chemistry is both science and art. The science of medicinal chemistry offers mankind one of its best hopes for improving the quality of life. The art of medicinal chemistry continues to challenge its practitioners with the need for both intuition and experience to discover new drugs. Hence...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
Άλλοι συγγραφείς: McAlpine, Shelli R. (Επιμελητής έκδοσης), Edkins, Adrienne Lesley (Επιμελητής έκδοσης)
Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
Γλώσσα:English
Έκδοση: Cham : Springer International Publishing : Imprint: Springer, 2016.
Έκδοση:1st ed. 2016.
Σειρά:Topics in Medicinal Chemistry, 19
Θέματα:
Διαθέσιμο Online:Full Text via HEAL-Link
Πίνακας περιεχομένων:
  • Targeting the C-Terminus of Hsp90 as a Cancer Therapy
  • Hsp90 Co-chaperones as Drug Targets in Cancer: Current Perspectives
  • Evaluating Dual Hsp90 and Hsp70 Inhibition as a Cancer Therapy
  • The Effect of Structure and Mechanism of the Hsp70 Chaperone on the Ability to Identify Chemical Modulators and Therapeutics
  • Allosteric Inhibitors of Hsp70: Drugging the Second Chaperone of Tumorigenesis
  • Hsp40 Co-chaperones as Drug Targets: Towards the Development of Specific Inhibitors
  • HSP47: The New Heat Shock Protein Therapeutic Target
  • Heat Shock Protein 27: Structure, Function, Cellular Role and Inhibitors.