Protein Targeting Compounds Prediction, Selection and Activity of Specific Inhibitors /

This book presents an overview of the most relevant protein knockdown techniques. Readers will find a description of the generation and use of recombinant human antibodies, ER intrabodies and peptides as well as a description of the working mechanism and potential of the inhibitory action of each of...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
Άλλοι συγγραφείς: Böldicke, Thomas (Επιμελητής έκδοσης)
Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
Γλώσσα:English
Έκδοση: Cham : Springer International Publishing : Imprint: Springer, 2016.
Σειρά:Advances in Experimental Medicine and Biology, 917
Θέματα:
Διαθέσιμο Online:Full Text via HEAL-Link
Πίνακας περιεχομένων:
  • Introduction
  • Part I Methods of Structure Prediction
  • Chapter 1 In Silico Prediction of Target-Inhibitor Interactions
  • Part II Antibodies
  • Chapter 2 Antibodies and Selection of Monoclonal Antibodies
  • Chapter 3 Selection of Recombinant Human Antibodies
  • Chapter 4 Selection of Recombinant Human Antibodies against Toxins and Viruses
  • Chapter 5 Recent Advances with ER Targeted Intrabodies
  • Chapter 6 Therapeutic Blocking Antibodies against Oncogenic Receptors and Growth Factors
  • Chapter 7 Synthetic Cystine-Knot Miniproteins-Valuable Scaffolds for Polypeptide Engineering
  • Part III Peptides, Small Molecules and Aptamers
  • Chapter 8 Peptides and Peptide Analogs to Inhibit Protein
  • Chapter 9 Allosteric Modulators of the Class A G Protein coupled Receptors
  • Chapter 10 Phosphatases: Their Roles in Cancer and their Chemical Modulators
  • Chapter 11 Selection and Application of Aptamers and Intramers
  • Part IV Angiogenesis Inhibitors
  • Chapter 12 Inhibitors of Angiogenesis.