PI3K-mTOR in Cancer and Cancer Therapy

• Corporate Author: SpringerLink (Online service)
• Other Authors: Dey, Nandini (Editor), De, Pradip (Editor), Leyland-Jones, Brian (Editor)
• Format: Electronic eBook
• Language: English
• Published: Cham : Springer International Publishing : Imprint: Humana Press, 2016.
• Series: Cancer Drug Discovery and Development,
• Subjects: Medicine.; Cancer research.; Drug resistance.; Molecular biology.; Biomedicine.; Cancer Research.; Molecular Medicine.; Drug Resistance.

In the post human-genome project era, cancer specific genomic maps are redesigning tumor taxonomy by evolving from histopathology to molecular pathology. The success of a cancer drug today is fundamentally based on the success in identifying target genes that control beneficial pathways. The overwhe...