Copper-Catalyzed Electrophilic Amination of sp2 and sp3 C−H Bonds

• Κύριος συγγραφέας: McDonald, Stacey L. (Συγγραφέας)
• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Cham : Springer International Publishing : Imprint: Springer, 2016.
• Σειρά: Springer Theses, Recognizing Outstanding Ph.D. Research,
• Θέματα: Chemistry.; Organometallic chemistry.; Chemical engineering.; Medicinal chemistry.; Organometallic Chemistry.; Medicinal Chemistry.; Industrial Chemistry/Chemical Engineering.

This thesis reports the latest developments in the direct amination of various C−H bonds using an H−Zn exchange/electrophilic amination strategy. McDonald and co-workers reveal this approach to be a rapid and powerful method for accessing a variety of functionalized amines. The material outlined in...

Πίνακας περιεχομένων:

• Electrophilic amination for the synthesis of alkyl and aryl amines
• Selective α-amination and α-acylation of esters and amides via dual reactivity of O-acylhydroxylamines toward zinc enolates
• Copper-catalyzed α-amination of phosphonates and phosphine oxides: a direct approach to α-amino phosphonic acids and derivatives
• Copper-Catalyzed Electrophilic Amination of Heteroarenes and Arenes by C−H Zincation.