Apoptosis in Cancer Pathogenesis and Anti-cancer Therapy New Perspectives and Opportunities /

This book discusses properties of apoptosis and other cell death modalities in cancer pathogenesis and treatment. Its nine chapters discuss modulation of anti-tumor inflammatory and immune responses, effects on the tumor microenvironment, to strategies for improving pro-apoptotic therapies, mechanis...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
Άλλοι συγγραφείς: Gregory, Christopher D. (Επιμελητής έκδοσης)
Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
Γλώσσα:English
Έκδοση: Cham : Springer International Publishing : Imprint: Springer, 2016.
Σειρά:Advances in Experimental Medicine and Biology, 930
Θέματα:
Διαθέσιμο Online:Full Text via HEAL-Link
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245 1 0 |a Apoptosis in Cancer Pathogenesis and Anti-cancer Therapy  |h [electronic resource] :  |b New Perspectives and Opportunities /  |c edited by Christopher D. Gregory. 
264 1 |a Cham :  |b Springer International Publishing :  |b Imprint: Springer,  |c 2016. 
300 |a XVII, 247 p. 29 illus., 28 illus. in color.  |b online resource. 
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490 1 |a Advances in Experimental Medicine and Biology,  |x 0065-2598 ;  |v 930 
505 0 |a Foreword -- Preface -- 1. Molecular Cell Biology of Apoptosis and Necroptosis in Cancer -- 2. Clearance of Dying Cells by Phagocytes: Mechanisms and Implications for Disease Pathogenesis -- 3. Micro-environmental Effects of Cell Death in Malignant Disease -- 4. Apoptotic Caspases in Promoting Cancer: Implications from Their Roles in Development and Tissue Homeostasis -- 5. Axl and Mer Receptor Tyrosine Kinases: Distinct and Non-overlapping Roles in Inflammation and Cancer? -- 6. Immunogenic Apoptotic Cell Death and Anti-cancer Immunity -- 7. Cancer Cell Death-inducing Radiotherapy – Impact on Local Tumour Control, Tumour Cell Proliferation and Induction of Systemic Anti-tumour Immunity -- 8. Novel Approaches to Apoptosis-inducing Therapies -- 9. Killing Is Not Enough – How Apoptosis Hijacks Tumor-associated Macrophages to Promote Cancer Progression -- Index. 
520 |a This book discusses properties of apoptosis and other cell death modalities in cancer pathogenesis and treatment. Its nine chapters discuss modulation of anti-tumor inflammatory and immune responses, effects on the tumor microenvironment, to strategies for improving pro-apoptotic therapies, mechanisms and implications for disease pathogenesis, axl and mer receptor tyrosine kinases, immunogenic apoptotic cell death and anti-cancer immunity and cancer cell death-inducing radiotherapy. This book places the onco-biology of apoptosis in clear and objective perspective through an expertly synthesized series of reviews. Apoptosis in Cancer Pathogenesis and Anti-cancer Therapy is a deft and thorough exploration of cutting-edge research in apoptosis and anti-cancer mechanisms from basic biology to oncology. It highlights a rapidly growing field within cancer research and is essential reading for oncologists, biochemists and advanced graduate students alike. 
650 0 |a Medicine. 
650 0 |a Cancer research. 
650 0 |a Molecular biology. 
650 0 |a Apoptosis. 
650 1 4 |a Biomedicine. 
650 2 4 |a Cancer Research. 
650 2 4 |a Apoptosis. 
650 2 4 |a Molecular Medicine. 
700 1 |a Gregory, Christopher D.  |e editor. 
710 2 |a SpringerLink (Online service) 
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776 0 8 |i Printed edition:  |z 9783319394046 
830 0 |a Advances in Experimental Medicine and Biology,  |x 0065-2598 ;  |v 930 
856 4 0 |u http://dx.doi.org/10.1007/978-3-319-39406-0  |z Full Text via HEAL-Link 
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