Apoptosis in Cancer Pathogenesis and Anti-cancer Therapy New Perspectives and Opportunities /

• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Άλλοι συγγραφείς: Gregory, Christopher D. (Επιμελητής έκδοσης)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Cham : Springer International Publishing : Imprint: Springer, 2016.
• Σειρά: Advances in Experimental Medicine and Biology, 930
• Θέματα: Medicine.; Cancer research.; Molecular biology.; Apoptosis.; Biomedicine.; Cancer Research.; Molecular Medicine.

This book discusses properties of apoptosis and other cell death modalities in cancer pathogenesis and treatment. Its nine chapters discuss modulation of anti-tumor inflammatory and immune responses, effects on the tumor microenvironment, to strategies for improving pro-apoptotic therapies, mechanis...

Πίνακας περιεχομένων:

• Foreword
• Preface
• 1. Molecular Cell Biology of Apoptosis and Necroptosis in Cancer
• 2. Clearance of Dying Cells by Phagocytes: Mechanisms and Implications for Disease Pathogenesis
• 3. Micro-environmental Effects of Cell Death in Malignant Disease
• 4. Apoptotic Caspases in Promoting Cancer: Implications from Their Roles in Development and Tissue Homeostasis
• 5. Axl and Mer Receptor Tyrosine Kinases: Distinct and Non-overlapping Roles in Inflammation and Cancer?
• 6. Immunogenic Apoptotic Cell Death and Anti-cancer Immunity
• 7. Cancer Cell Death-inducing Radiotherapy – Impact on Local Tumour Control, Tumour Cell Proliferation and Induction of Systemic Anti-tumour Immunity
• 8. Novel Approaches to Apoptosis-inducing Therapies
• 9. Killing Is Not Enough – How Apoptosis Hijacks Tumor-associated Macrophages to Promote Cancer Progression
• Index.