Evolution of the Protein Synthesis Machinery and Its Regulation

• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Άλλοι συγγραφείς: Hernández, Greco (Επιμελητής έκδοσης), Jagus, Rosemary (Επιμελητής έκδοσης)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Cham : Springer International Publishing : Imprint: Springer, 2016.
• Θέματα: Life sciences.; Biochemistry.; Plant biochemistry.; Proteins.; Cell biology.; Evolutionary biology.; Life Sciences.; Protein Science.; Evolutionary Biology.; Cell Biology.; Plant Biochemistry.; Animal Biochemistry.; Animal Systematics/Taxonomy/Biogeography.

 The “omics” era has given a new perspective to the findings on the origin and evolution of the process of translation. This book provides insight into the evolution of the translation process and machinery from a modern perspective. Written by leading experts in molecular biology, this text looks into the origins and evolution of the protein synthetic machinery. 

 A review on the origin of the different codes for translation -- Evolution of ribosomes -- Origins and early evolution of ribosomes -- Evolution of ribosomes and ribosomal proteins -- Evolution of Class II aminoacyl synthetases from the antisense of the genes for Class I -- The translation process during the evolutionary transition from prokaryotes to eukaryotes -- Evolution of translational control: from archaea to eukarya -- Distribution of elongation family GTPases EF1A and EFL in basal alveolate lineages -- Evolution of mRNA structure; the eukaryotic mRNA 5´- and 3´- untranslated regions and their role in translational regulation -- How lower eukaryotes contribute on our understanding of eIF4E-dependent translation -- Evolution of functionally divergent eIF4Es and their roles in the regulation of mRNA recruitment and developmental processes -- Evolution of eIF4E and eIF4G interactions in trypanosomes -- Evolution of the functionally divergent eIF4E family members in deuterostomes -- Evolution of the eIF2alpha kinases and translational control -- Evolution and use of eIF2alpha kinases in the apicomplexans and their role in life history of the parasites Plasmodium falciparum and Toxoplasma gondii -- Evolution of the TOR pathway and translational regulation -- Origin and diversification of eIF4E-binding proteins -- Evolution of the protein synthesis machinery in mitochondria -- Relationship between plant translation initiation factors and RNA viruses: An evolutionary perspective -- Evolution of miRNAs and RNA binding proteins in eukaryotes -- Evolution of silencing foci across eukaryotes -- Evolutionary conservation of the machineries coupling RNA transport with translation in eukaryotes.