Nanoscale Imaging and Characterisation of Amyloid-β

• Main Author: Tinker-Mill, Claire Louisa (Author)
• Corporate Author: SpringerLink (Online service)
• Format: Electronic eBook
• Language: English
• Published: Cham : Springer International Publishing : Imprint: Springer, 2016.
• Series: Springer Theses, Recognizing Outstanding Ph.D. Research,
• Subjects: Physics.; Molecular biology.; Neurology.; Amorphous substances.; Complex fluids.; Spectroscopy.; Microscopy.; Nanotechnology.; Spectroscopy and Microscopy.; Soft and Granular Matter, Complex Fluids and Microfluidics.; Molecular Medicine.

This thesis presents a method for reliably and robustly producing samples of amyloid-β (Aβ) by capturing them at various stages of aggregation, as well as the results of subsequent imaging with various atomic force microscopy (AFM) methods, all of which add value to the data gathered by collecting i...