Novel Therapeutic Approaches to the Treatment of Parkinson’s Disease An Overview and Update /

• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Άλλοι συγγραφείς: Hopkins, Corey R. (Επιμελητής έκδοσης)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Cham : Springer International Publishing : Imprint: Springer, 2016.
• Σειρά: Topics in Medicinal Chemistry, 18
• Θέματα: Chemistry.; Molecular biology.; Neurochemistry.; Medicinal chemistry.; Medical biochemistry.; Proteins.; Medicinal Chemistry.; Medical Biochemistry.; Receptors.; Molecular Medicine.

 Medicinal chemistry is both science and art. The science of medicinal chemistry offers mankind one of its best hopes for improving the quality of life. The art of medicinal chemistry continues to challenge its practitioners with the need for both intuition and experience to discover new drugs. Hence sharing the experience of drug research is uniquely beneficial to the field of medicinal chemistry. Drug research requires interdisciplinary team-work at the interface between chemistry, biology and medicine. Therefore, the topic-related series Topics in Medicinal Chemistry covers all relevant aspects of drug research, e.g. pathobiochemistry of diseases, identification and validation of (emerging) drug targets, structural biology, drugability of targets, drug design approaches, chemogenomics, synthetic chemistry including combinatorial methods, bioorganic chemistry, natural compounds, high-throughput screening, pharmacological in vitro and in vivo investigations, drug-receptor interactions on the molecular level, structure-activity relationships, drug absorption, distribution, metabolism, elimination, toxicology and pharmacogenomics. In general, special volumes are edited by well known guest editors. 

 Adenosine A2A Receptor Antagonists -- Targeting α-Synuclein as a Parkinson’s Disease Therapeutic -- Leucine-Rich Repeat Kinase 2 (LRRK2) Inhibitors.