Increasing the Therapeutic Ratio of Radiotherapy

• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Άλλοι συγγραφείς: Tofilon, Philip J. (Επιμελητής έκδοσης), Camphausen, Kevin (Επιμελητής έκδοσης)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Cham : Springer International Publishing : Imprint: Humana Press, 2017.
• Σειρά: Cancer Drug Discovery and Development,
• Θέματα: Medicine.; Cancer research.; Drug resistance.; Radiotherapy.; Biomedicine.; Cancer Research.; Drug Resistance.

Current cancer therapies are focused on three general strategies: modifying intrinsic radiosensitivity via molecular targeting, manipulating microenvironmental factors to enhance tumor susceptibility to radiation, and improving delivery of radiation to critical tumor locations while sparing normal t...

Πίνακας περιεχομένων:

• Part 1. Molecular Targets
• 1. Improving the therapeutic ratio of radiotherapy by targeting the DNA Damage Response
• 2. Receptor Tyrosine Kinases as Targets for Enhancing Tumor Radiosensitivity
• 3. Histone Deacetylase Inhibitors and Tumor Radiosensitization
• 4. Radioprotection as a Method to Enhance the Therapeutic Ratio of Radiotherapy
• Part 2. Microenvironment
• 5. Application of Functional Molecular Imaging in Radiation Oncology
• 6. Remodeling the Irradiated Tumor Microenvironment: The 5th R of Radiobiology?
• 7. Combining Radiotherapy and Immunotherapy: Emerging Preclinical Observations of Lymphocyte Costimulatory and Inhibitory Receptor Modulation
• Part 3. Clinical
• 8. Stereotactic Body Radiation Therapy (SBRT) or Alternative Fractionation Schedules
• 9. Novel Imaging for Treatment Planning or Tumor Response
• 10. Increasing the Therapeutic Efficacy of Radiotherapy Using Nanoparticles
• Index.