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02949nam a22004935i 4500 |
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978-3-319-41171-2 |
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DE-He213 |
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20160726135514.0 |
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cr nn 008mamaa |
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160726s2016 gw | s |||| 0|eng d |
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|a 9783319411712
|9 978-3-319-41171-2
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|a 10.1007/978-3-319-41171-2
|2 doi
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|a QR46
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|a MMFM
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|a MED052000
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|a 616.9041
|2 23
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|a Inflammasome Signaling and Bacterial Infections
|h [electronic resource] /
|c edited by Steffen Backert.
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|a Cham :
|b Springer International Publishing :
|b Imprint: Springer,
|c 2016.
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| 300 |
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|a XI, 282 p. 29 illus., 28 illus. in color.
|b online resource.
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|a text
|b txt
|2 rdacontent
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|a computer
|b c
|2 rdamedia
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|a online resource
|b cr
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|a text file
|b PDF
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|a Current Topics in Microbiology and Immunology,
|x 0070-217X ;
|v 397
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| 520 |
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|a This volume details our current understanding of the architecture and signaling capabilities of known canonical and non-canonical inflammasome complexes and highlights their action, in particular in response to infection with important bacterial model organisms and the corresponding disease pathologies. The first chapters review new insights into the assembly and structures of inflammasome components and emphasize general strategies of up- and downstream signaling events. In addition, the authors specifically discuss the composition and activity of inflammasomes during infection with various gut pathogens (Salmonella, Shigella, Yersinia, Listeria and Helicobacter), respiratory pathogens (Mycobacterium, Legionella, Burkholderia and Streptococcus) as well as skin and soft tissue pathogens (Francisella and Staphylococcus). The discoveries presented provide a better understanding of the cellular and molecular biology of inflammasomes, which will pinpoint important new therapeutic targets for the treatment and prevention of multiple infectious diseases in the future. It is a valuable resource for students, scientists and clinicians, providing up-to-date information on this emerging research topic.
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|a Medicine.
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|a Medical microbiology.
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|a Parasitology.
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|a Infectious diseases.
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|a Respiratory organs
|x Diseases.
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|a Biomedicine.
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| 650 |
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|a Medical Microbiology.
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| 650 |
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4 |
|a Infectious Diseases.
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| 650 |
2 |
4 |
|a Parasitology.
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| 650 |
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4 |
|a Pneumology/Respiratory System.
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| 700 |
1 |
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|a Backert, Steffen.
|e editor.
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| 710 |
2 |
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|a SpringerLink (Online service)
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|t Springer eBooks
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|i Printed edition:
|z 9783319411705
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| 830 |
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|a Current Topics in Microbiology and Immunology,
|x 0070-217X ;
|v 397
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| 856 |
4 |
0 |
|u http://dx.doi.org/10.1007/978-3-319-41171-2
|z Full Text via HEAL-Link
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| 912 |
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|a ZDB-2-SBL
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| 950 |
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|a Biomedical and Life Sciences (Springer-11642)
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