Polymer Nanoparticles for Nanomedicines A Guide for their Design, Preparation and Development /

• Corporate Author: SpringerLink (Online service)
• Other Authors: Vauthier, Christine (Editor), Ponchel, Gilles (Editor)
• Format: Electronic eBook
• Language: English
• Published: Cham : Springer International Publishing : Imprint: Springer, 2016.
• Subjects: Medicine.; Pharmaceutical technology.; Biomedical engineering.; Pharmacy.; Proteomics.; Biomedicine.; Pharmaceutical Sciences/Technology.; Drug Safety and Pharmacovigilance.; Biomedical Engineering/Biotechnology.

Nanomedicines comprise a wide range of nanotechnologies including various types of nanoparticles developed as therapeutic, diagnostic and theranostic agents. The translation of nanoparticles in the clinical setting is rapidly progressing. It is now a quite well-established idea that the ultimate in...

Table of Contents:

• Preface
• Introduction Part I: Polymer nanoparticles for in vivo applications: Progress on preparation methods and future challenges
• Nanoprecipitation process: From particlepreparation to in vivo applications
• Targeted Theragnostic Nanoparticles via Flash Nanoprecipitation: Principles of Materials Selection
• Preparation of polymer nanoparticles by the emulsification-solvent evaporation method: from Vanderhoff´s pioneer approach to recent adaptations
• Methods for the preparation of nanoparticles by polymerization
• Shape-controlled nanoparticles for drug delivery and targeting applications
• Physicochemical characterization of polymer nanoparticles: Challenges and present limitations
• Imaging polymer nanoparticles by means of transmission and scanning electron microscopy techniques
• Evaluating the interactions between proteins and components of the immune system with polymer nanoparticles
• Investigating interactions between nanoparticles and cells: internalization and intracellular trafficking
• Characterization of mucoadhesive interactions between nanoparticles and epithelial membranes
• Designing polymer nanoparticle nanomedicines: potential applications and challenges
• Selecting and designing polymers suitable for nanoparticles manufacturing
• Associating Drugs with Polymer Nanoparticles: A Challenge
• Drug delivery by nanoparticles: The Challenge of Controlled Release and Evaluation
• Interaction between nanoparticles and plasma proteins: effects on nanoparticle biodistribution and toxicity
• Toxicological aspects of polymer nanoparticles
• Theranostics: In Vivo
• Nanomedicines –A scientific toy or an emerging market?
• Regulatory perspective on the development of polymeric nanomaterials.