Protein Therapeutics

• Corporate Author: SpringerLink (Online service)
• Other Authors: Sauna, Zuben E. (Editor), Kimchi-Sarfaty, Chava (Editor)
• Format: Electronic eBook
• Language: English
• Published: Cham : Springer International Publishing : Imprint: Springer, 2017.
• Series: Topics in Medicinal Chemistry, 21
• Subjects: Chemistry.; Medicinal chemistry.; Proteins.; Biomedical engineering.; Medicinal Chemistry.; Biomedical Engineering.; Protein Science.

Medicinal chemistry is both science and art. The science of medicinal chemistry offers mankind one of its best hopes for improving the quality of life. The art of medicinal chemistry continues to challenge its practitioners with the need for both intuition and experience to discover new drugs. Hence...

Table of Contents:

• Protein Production in Eukaryotic Cells
• Production of Protein Therapeutics in the Quality by Design (QbD) Paradigm
• Characterization of Therapeutic Proteins
• Immunogenicity Lessons Learned from the Clinical Development of Vatreptacog Alfa, A Recombinant Activated Factor VII Analog, in Hemophilia with Inhibitors
• The Art of Gene Redesign and Recombinant Protein Production: Approaches and Perspectives.