Non-coding RNAs in Colorectal Cancer

This is the first book to provide a broad framework for obtaining an in depth understanding of the state-of-the-art knowledge on abnormalities of non-coding RNAs found to be associated with colorectal cancer pathogenesis. Readers will discover possible mechanisms underlying the substantial roles pla...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
Άλλοι συγγραφείς: Slaby, Ondrej (Επιμελητής έκδοσης), Calin, George A. (Επιμελητής έκδοσης)
Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
Γλώσσα:English
Έκδοση: Cham : Springer International Publishing : Imprint: Springer, 2016.
Σειρά:Advances in Experimental Medicine and Biology, 937
Θέματα:
Διαθέσιμο Online:Full Text via HEAL-Link
Πίνακας περιεχομένων:
  • Introduction.-Part I Non-coding RNAs: biology and implications in colorectal cancer pathogenesis.-Non-coding RNAs: classification, biology and functioning.-Involvement of non-coding RNAs in hallmarks and key signaling pathways of colorectal cancer.-MicroRNAs and inflammation in colorectal cancer
  • Interplay between transcription factors and microRNAs regulating epithelial-mesenchymal transitions in colorectal cancer
  • Non-coding RNAs functioning in colorectal cancer stem cells
  • MicroRNA Methylation in Colorectal Cancer
  • Polymorphisms in non-coding RNA genes and their targets sites as risk factors of sporadic colorectal cancer
  • Part II Non-coding RNAs: new class of biomarkers in colorectal cancer
  • Non-coding RNAs as biomarkers for colorectal cancer screening and early detection
  • Circulating non-coding RNAs as biomarkers in colorectal cancer
  • Non-coding RNAs enabling prognostic stratification and prediction of therapeutic response in colorectal cancer patients
  • Part III Non-coding RNAs: therapeutic targets and colorectal cancer therapeutics
  • Involvement of non-coding RNAs in chemo- and radioresistance of colorectal cancer
  • Non-coding RNAs: therapeutic strategies and delivery systems
  • MicroRNAs as therapeutic targets and colorectal cancer therapeutics
  • Summary
  • Index. .