Mitochondrial Mechanisms of Degeneration and Repair in Parkinson's Disease

This volume brings together various theories of how aberrations in mitochondrial function and morphology contribute to neurodegeneration in idiopathic and familial forms of Parkinson’s disease. Moreover, it comprehensively reviews the current search for therapies, and proposes how molecules are invo...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
Άλλοι συγγραφείς: Buhlman, Lori M. (Επιμελητής έκδοσης)
Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
Γλώσσα:English
Έκδοση: Cham : Springer International Publishing : Imprint: Springer, 2016.
Θέματα:
Διαθέσιμο Online:Full Text via HEAL-Link
Πίνακας περιεχομένων:
  • Mitochondrial ROS and Apoptosis
  • Dopamine Metabolism and Reactive Oxygen Species Production
  • The Consequences of Damaged Mitochondrial DNA
  • The role of chronic inflammation in the etiology of Parkinson’s disease
  • Ion-Catalyzed Reactive Oxygen Species in Sporadic Models of Parkinson's Disease
  • Toxin Mediated Complex I Inhibition and Parkinson’s Disease
  • Parkinson Disease-Associated Mutations Affect Mitochondrial Function
  • PARKIN/PINK1 Pathway for the Selective Isolation and Degradation of Impaired Mitochondria
  • Mitochondrial Therapeutic approaches in Parkinson's Disease
  • Altering Mitochondrial Fusion and Fission Protein Levels Rescues Parkin and PINK1 Loss-of-Function Phenotypes
  • Early Nicotine Exposure is Protective in Familial and Idiopathic Models of Parkinson’s Disease
  • Transcription Modulation of Mitochondrial Function and Related Pathways as a Therapeutic Opportunity in Parkinson’s Disease
  • Delivery of Biologically Active Molecules to Mitochondria.