Small Animal Imaging Basics and Practical Guide /
This textbook is a practical guide to the use of small animal imaging in preclinical research that will assist in the choice of imaging modality and contrast agent and in study design, experimental setup, and data evaluation. All established imaging modalities are discussed in detail, with the assis...
| Συγγραφή απο Οργανισμό/Αρχή: | |
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| Άλλοι συγγραφείς: | , , |
| Μορφή: | Ηλεκτρονική πηγή Ηλ. βιβλίο |
| Γλώσσα: | English |
| Έκδοση: |
Cham :
Springer International Publishing : Imprint: Springer,
2017.
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| Έκδοση: | 2nd ed. 2017. |
| Θέματα: | |
| Διαθέσιμο Online: | Full Text via HEAL-Link |
Πίνακας περιεχομένων:
- Part I Role of small animal imaging: Non invasive imaging for supporting basic research
- Non invasive imaging in the pharmaceutical industry
- How to set up a small animal imaging unit
- Significance of non invasive imaging for animal protection
- Animal Models: From zebrafish to non human primates. Part II Study planning and animal preparation: Institutional preconditions for small animal imaging
- Statistical considerations for animal imaging studies
- Animal anesthesia and monitoring
- Drug administration. Part III Imaging modalities and probes: How to choose the right imaging modality
- How to identify suitable Biomarkers
- Concepts in diagnostic probe design
- X-ray and X-ray-CT
- CT contrast agents
- MR contrast agents
- MRS
- Hyperpolarized MRI
- Ultrasound
- Ultrasound contrast agents
- PET and SPECT
- Radiotracer I: Standard tracer
- Radiotracer II: Peptide-based radiopharmaceuticals
- Optical imaging
- Photoacoustic imaging
- Optical probes
- Multimodal imaging and image fusion. Part IV Ex vivo validation methods:Methods for correlation between in vivo small ani-mal images and post mortem data: example brain
- In Vitro Methods for In Vivo Quantitation of PET and SPECT Imaging Probes: Autoradiography and Gamma Counting. Part V: Data postprocessing: Qualitative and quantitative data analysis
- Guidelines for nuclear image analysis
- Kinetic modeling
- Data documentation systems. Part VI: Special applications:Imaging in drug safety Evaluation
- Cell tracking and transplant imaging
- Imaging of metabolic diseases
- Imaging in developmental biology
- Imaging in gynecology research
- Imaging in cardiovascular research
- Imaging in neurology research I: Neuoroncology
- Imaging in neurology research II: Plasticity and cognitive networks
- Imaging in neurology research III: Neurodegenerative diseases
- Neurooptogenetics
- Imaging in oncology research
- Imaging in immunology research
- Imaging of infectious diseases. .
