STAT Inhibitors in Cancer

• Corporate Author: SpringerLink (Online service)
• Other Authors: Ward, Alister C. (Editor)
• Format: Electronic eBook
• Language: English
• Published: Cham : Springer International Publishing : Imprint: Humana Press, 2016.
• Series: Cancer Drug Discovery and Development,
• Subjects: Medicine.; Cancer research.; Biomedicine.; Cancer Research.

This volume, which includes contributions from leading scientists and clinicians in the field, provides definitive, state-of-the-art information on STAT inhibitors in a biological and clinical context. It gives an overview of the biology of the STAT family of transcription factors and their role in...

Table of Contents:

• STATs in Health and Disease
• STAT Proteins in Cancer
• Translating STAT Inhibitors from the Lab to the Clinic
• Historical Development of STAT3 Inhibitors and Early Results in Clinical Trials
• STAT3 Inhibitors in Cancer: A Comprehensive Update
• Targeting Upstream Janus Kinases
• Inhibitors of Upstream Inducers of STAT Activation.