Disordered Vertebral and Rib Morphology in Pudgy Mice Structural Relationships to Human Congenital Scoliosis /
This book presents results obtained from the whole mount preparations, radiological, and histological studies of 60 pu/pu and pu/+ mice from late embryo until 3 months of age. Most mice were in the embryo to 6 week age group where vertebral developmental changes are most marked. Although vertebral a...
| Κύριος συγγραφέας: | |
|---|---|
| Συγγραφή απο Οργανισμό/Αρχή: | |
| Μορφή: | Ηλεκτρονική πηγή Ηλ. βιβλίο |
| Γλώσσα: | English |
| Έκδοση: |
Cham :
Springer International Publishing : Imprint: Springer,
2016.
|
| Σειρά: | Advances in Anatomy, Embryology and Cell Biology,
221 |
| Θέματα: | |
| Διαθέσιμο Online: | Full Text via HEAL-Link |
Πίνακας περιεχομένων:
- I. INTRODUCTION
- II. MATERIALS AND METHODS
- 1. Source, distribution, and ages of pudgy and non-affected mice. - 2. Whole mount preparations
- 3. Radiographic studies
- 4. Histologic studies
- 5. Computerized three-dimensional reconstructions
- 6. Previous studies on chick vertebral development and human congenital scoliosis
- III. RESULTS
- 1. Gross appearance
- 2. Whole mount appearances
- 3. Radiographic studies
- 4. Histology studies: vertebrae, ribs, intervertebral discs and ganglia
- 5. Computerized three-dimensional reconstructions
- 6. Chick embryo vertebral development
- 7. Radiology and histopathology of human congenital scoliosis spine
- IV. DISCUSSION
- ion
- 3. The pudgy mouse
- 4. Genetic influences on axial development; mutations identified in mouse models with vertebral deformation
- 5. Congenital scoliosis (human); its similarity with pudgy mouse vertebral abnormalities
- 6. Pathogenesis of pudgy and human congenital scoliosis based on histopathologic studies.-V. CONCLUSIONS
- 1. Implications of pudgy vertebral abnormalities for biologic research
- 2. Implications of pudgy vertebral abnormalities for clinical patient treatment. .
