Skin Stress Response Pathways Environmental Factors and Molecular Opportunities /

• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Άλλοι συγγραφείς: Wondrak, Georg T. (Επιμελητής έκδοσης)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Cham : Springer International Publishing : Imprint: Springer, 2016.
• Θέματα: Medicine.; Biomedicine.; Biomedicine general.

It is now established that the interplay between environmental exposure and molecular stress response pathways plays a critical role in skin health and disease, and a refined mechanistic understanding of this phenomenon at the molecular level promises to open new avenues for targeted therapeutic str...

Πίνακας περιεχομένων:

• Preface
• The skin lipidome under environmental stress – Technological platforms, molecular pathways and translational opportunities
• Squalene and skin barrier function: From molecular target to biomarker of environmental exposure
• Sunlight-induced DNA damage: molecular mechanisms and photoprotection strategies
• Urocanic Acid and Skin Photodamage: New Light on an Old Chromophore
• The Skin Extracellular Matrix as a Target of Environmental Exposure: Molecular Mechanisms, Prevention and Repair
• Nitric Oxide Derivatives and Skin Environmental Exposure to light: From Molecular Pathways to Therapeutic Opportunities
• Melanocortin 1 receptor (MC1R) as a global regulator of cutaneous UV responses: molecular interactions and opportunities for melanoma prevention
• The Cutaneous Melanocyte as a Target of Environmental Stressors: Molecular Mechanisms and Opportunities
• The Role of Epidermal p38 Signaling in Solar UV Radiation-induced Inflammation: Molecular Pathways and Preventive Opportunities
• UV-Induced Chemokines as Emerging Targets for Skin Cancer Photochemoprevention
• TLR3 and Inflammatory Skin Diseases: From Environmental Factors to Molecular Opportunities
• Sirtuins and stress response in skin cancer, aging, and barrier function
• Cutaneous Opioid Receptors and Stress Responses: Molecular Interactions and Opportunities for Therapeutic Intervention
• Regulation of Cutaneous Stress Response Pathways by the Circadian Clock: From Molecular Pathways to Therapeutic Opportunities
• Endocannabinoids and Skin Barrier Function: Molecular Pathways and Therapeutic Opportunities
• The aryl hydrocarbon receptor (AhR) as an environmental stress sensor and regulator of skin barrier function: Molecular mechanisms and therapeutic opportunities
• Biological cell protection by natural compounds, a second line of defense against solar radiation
• The Cutaneous Microbiota as a Determinant of Skin Barrier Function: Molecular Interactions and Therapeutic Opportunities
• Sensing Environmental Factors: The Emerging Role of Receptors in Epidermal Homeostasis and Whole-Body Health
• The Cutaneous Circadian Clock as a Determinant of Environmental Vulnerability: Molecular Pathways and Chrono-pharmacological Opportunities
• Psychological stress as a determinant of skin barrier function: Immunological pathways and therapeutic opportunities
• Index.