The Ageing Immune System and Health

The present book intends to provide an update on immunosenescence and how deficiencies in the immune system contribute to a higher susceptibility to infections, decline in organ function, reduced vaccination responses, age-related disease and the ageing process itself, negatively affecting longevity...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
Άλλοι συγγραφείς: Bueno, Valquiria (Επιμελητής έκδοσης), Lord, Janet M. (Επιμελητής έκδοσης), Jackson, Thomas A. (Επιμελητής έκδοσης)
Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
Γλώσσα:English
Έκδοση: Cham : Springer International Publishing : Imprint: Springer, 2017.
Θέματα:
Διαθέσιμο Online:Full Text via HEAL-Link
Πίνακας περιεχομένων:
  • 1. Introduction
  • 2. Innate Immune Response and Ageing (neutrophils, monocytes, dendritic cells, DAMPs, PAMPs
  • 3. Adaptive Immune Response and Aging (T and B lymphocytes, naïve, effector and memory phenotypes and functions)
  • 4. Modulatory/Suppressive Cells and Ageing (T regulatory cells, B regulatory cells, Myeloid Derived Suppressor Cells, Modulatory Neutrophils, M1 and M2 macrophages)
  • 5. Mucosal Immune System and Ageing
  • 6. Epigenetics and Ageing
  • 7. Cancer and Ageing
  • 8. Infections/Vaccination and Ageing
  • 9. Cytomegalovirus and immmunosenescence
  • 10. Frailty and Ageing
  • 11. Inflammation and Neurodegenerative Diseases and Ageing
  • 12. Effects of chronic inflammatory diseases (chronic kidney disease, rheumatoid arthritis, crohns disease etc) on the ageing of the immune system
  • 13. Interventions in Elderly focusing Immunosenescence (physical activity, nutrition, supplements).