Fundamentals of Pediatric Drug Dosing

• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Άλλοι συγγραφείς: Mahmood, Iftekhar (Επιμελητής έκδοσης), Burckart, Gilbert (Επιμελητής έκδοσης)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Cham : Springer International Publishing : Imprint: Adis, 2016.
• Θέματα: Medicine.; General practice (Medicine).; Pediatrics.; Pharmacotherapy.; Medicine & Public Health.; General Practice / Family Medicine.

Focused on pediatric physiology, pharmacology, pharmacokinetics and pharmacodynamics, this book illustrates the differences between the pediatric population and adults; knowledge of extreme importance not only during pediatric drug development but also in the clinical practice. Physicians, nurses, c...

Πίνακας περιεχομένων:

• 1. Pediatric Drug Development and the Regulatory Changes that are Creating the Science of Pediatric Dosing
• 2. Pediatric Physiology
• 3. Developmental Pharmacology: Impact on Pharmacokinetics and Pharmacodynamics of Drugs
• 4. Pediatric Clinical Trial Design and Dosing
• 5. Applicaton of Allometric Principles in Pediatric Drug Development
• 6. Population Pharmacokinetics in Pediatric Drug Development
• 7. Scaling Dose-Exposure-Response from Adults to Children
• 8. Applications of Physiologically-Based Pharmacokinetic (PBPK) Models for Pediatric Populations
• 9. Perinatal Pharmacology and Maternal/Fetal Dosing.