Dynamics and Mechanism of DNA-Bending Proteins in Binding Site Recognition

• Κύριος συγγραφέας: Velmurugu, Yogambigai (Συγγραφέας)
• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Cham : Springer International Publishing : Imprint: Springer, 2017.
• Σειρά: Springer Theses, Recognizing Outstanding Ph.D. Research,
• Θέματα: Physics.; Proteins.; Spectroscopy.; Microscopy.; Biological and Medical Physics, Biophysics.; Spectroscopy and Microscopy.; Protein-Ligand Interactions.

Using a novel approach that combines high temporal resolution of the laser T-jump technique with unique sets of fluorescent probes, this study unveils previously unresolved DNA dynamics during search and recognition by an architectural DNA bending protein and two DNA damage recognition proteins. Man...

Πίνακας περιεχομένων:

• Introduction
• Methods
• Integration Host Factor (IHF)-DNA interaction
• Lesion Recognition by Xeroderma Pigmentosum C (XPC) Protein
• DNA Mismatch Repair.