Pancreatic Islet Biology

• Corporate Author: SpringerLink (Online service)
• Other Authors: A. Hardikar, Anandwardhan (Editor)
• Format: Electronic eBook
• Language: English
• Published: Cham : Springer International Publishing : Imprint: Springer, 2016.
• Series: Stem Cell Biology and Regenerative Medicine,
• Subjects: Life sciences.; Diabetes.; Stem cells.; Regenerative medicine.; Tissue engineering.; Life Sciences.; Stem Cells.; Regenerative Medicine/Tissue Engineering.

This comprehensive volume discusses in vitro laboratory development of insulin-producing cells. It encompasses multiple aspects of islet biology—from embryonic development and stem cell differentiation to clinical studies in islet transplantation, regulation of islet beta-cell regeneration, pancreat...

Table of Contents:

• The Pathobiology of Diabetes Mellitus
• Comparative Analysis of Islet Development
• Mathematical Modeling of Islet Generation, Degeneration and Regeneration
• Epigenetic Regulation of Islet Development and Regeneration
• Pancreatic Regeneration after Partial Pancreatectomy in Rodents
• Regulators of Beta Cell Death and Regeneration
• MicroRNAs – A Link between Type 1 Diabetes and the Environment?
• Transdifferentiation of Extra-Pancreatic Tissues for Cell Replacement Therapy for Diabetes
• Generation of Human Islet Progenitor Cells via Epithelial to Mesenchymal Transition
• Viral-Mediated Gene Therapy in Generation of Insulin-Producing Cells for Treatment of Diabetes
• Regenerative Medicine: Clinical Islet Transplantation
• Beta Cell Therapies for Type 1 Diabetes.