Simple Mathematical Models of Gene Regulatory Dynamics

• Κύριοι συγγραφείς: Mackey, Michael C. (Συγγραφέας), Santillán, Moisés (Συγγραφέας), Tyran-Kamińska, Marta (Συγγραφέας), Zeron, Eduardo S. (Συγγραφέας)
• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Cham : Springer International Publishing : Imprint: Springer, 2016.
• Σειρά: Lecture Notes on Mathematical Modelling in the Life Sciences,
• Θέματα: Medicine.; Gene expression.; Systems biology.; Differential equations.; Applied mathematics.; Engineering mathematics.; Probabilities.; Biomathematics.; Biomedicine.; Gene Expression.; Mathematical and Computational Biology.; Systems Biology.; Applications of Mathematics.; Ordinary Differential Equations.; Probability Theory and Stochastic Processes.

This is a short and self-contained introduction to the field of mathematical modeling of gene-networks in bacteria. As an entry point to the field, we focus on the analysis of simple gene-network dynamics. The notes commence with an introduction to the deterministic modeling of gene-networks, with e...

Πίνακας περιεχομένων:

• Introduction
• Part I Deterministic Modeling Techniques
• 1.Generic deterministic models of prokaryotic gene regulation
• 2.General dynamic considerations
• Part II Dealing with Noise
• 3.Master equation modeling approaches
• 4.Noise effects in gene regulation: Intrinsic versus extrinsic
• Part III Specific Examples
• 5.The lactose operon
• 6.The tryptophan operon
• 7.The Lysis-Lysogeny Switch
• Index
• References.