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02478nam a22004455i 4500 |
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978-3-319-45397-2 |
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DE-He213 |
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20161209083304.0 |
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161209s2017 gw | s |||| 0|eng d |
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|a 9783319453972
|9 978-3-319-45397-2
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|a 10.1007/978-3-319-45397-2
|2 doi
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|d GrThAP
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|a RC261-271
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|a MJCL
|2 bicssc
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|a MED062000
|2 bisacsh
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|a 614.5999
|2 23
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|a Ex Vivo Engineering of the Tumor Microenvironment
|h [electronic resource] /
|c edited by Amir R. Aref, David Barbie.
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|a Cham :
|b Springer International Publishing :
|b Imprint: Humana Press,
|c 2017.
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|a IX, 135 p. 18 illus., 17 illus. in color.
|b online resource.
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|a text
|b txt
|2 rdacontent
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|a computer
|b c
|2 rdamedia
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|a online resource
|b cr
|2 rdacarrier
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|a text file
|b PDF
|2 rda
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|a Cancer Drug Discovery and Development,
|x 2196-9906
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|a 1.Introduction to Ex Vivo Cancer Models -- 2.Patient-derived Xenografts in Oncology -- 3.Organoid Culture: Applications in Development and Cancer -- 4. Microfluidics and future of cancer diagnostics -- 5.Advancing techniques and insights in circulating tumor cell (CTC) research -- 6.The Cancer Secretome -- 7.An overview of the tumor microenvironments and future of cancer therapy. .
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|a This volume will outline how to recreate the tumor microenvironment, to culture primary tumors without the need for developmental priming factors, and to deliver targeted therapeutics in a manner that recapitulates pharmacokinetics in vivo. Much of what may be learned from this volume will aid in understanding many aspects of the enhanced study of tumor cell biology in a physiologic context, open new avenues for drug screening and biomarker development, and accelerate the preclinical evaluation of novel personalized medicine strategies for patients in real time.
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650 |
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|a Medicine.
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|a Cancer research.
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|a Biomedicine.
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|a Cancer Research.
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700 |
1 |
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|a Aref, Amir R.
|e editor.
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1 |
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|a Barbie, David.
|e editor.
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710 |
2 |
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|a SpringerLink (Online service)
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773 |
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|t Springer eBooks
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776 |
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8 |
|i Printed edition:
|z 9783319453958
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830 |
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|a Cancer Drug Discovery and Development,
|x 2196-9906
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856 |
4 |
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|u http://dx.doi.org/10.1007/978-3-319-45397-2
|z Full Text via HEAL-Link
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912 |
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|a ZDB-2-SME
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950 |
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|a Medicine (Springer-11650)
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