Ex Vivo Engineering of the Tumor Microenvironment

This volume will outline how to recreate the tumor microenvironment, to culture primary tumors without the need for developmental priming factors, and to deliver targeted therapeutics in a manner that recapitulates pharmacokinetics in vivo. Much of what may be learned from this volume will aid in un...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
Άλλοι συγγραφείς: Aref, Amir R. (Επιμελητής έκδοσης), Barbie, David (Επιμελητής έκδοσης)
Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
Γλώσσα:English
Έκδοση: Cham : Springer International Publishing : Imprint: Humana Press, 2017.
Σειρά:Cancer Drug Discovery and Development,
Θέματα:
Διαθέσιμο Online:Full Text via HEAL-Link
LEADER 02478nam a22004455i 4500
001 978-3-319-45397-2
003 DE-He213
005 20161209083304.0
007 cr nn 008mamaa
008 161209s2017 gw | s |||| 0|eng d
020 |a 9783319453972  |9 978-3-319-45397-2 
024 7 |a 10.1007/978-3-319-45397-2  |2 doi 
040 |d GrThAP 
050 4 |a RC261-271 
072 7 |a MJCL  |2 bicssc 
072 7 |a MED062000  |2 bisacsh 
082 0 4 |a 614.5999  |2 23 
245 1 0 |a Ex Vivo Engineering of the Tumor Microenvironment  |h [electronic resource] /  |c edited by Amir R. Aref, David Barbie. 
264 1 |a Cham :  |b Springer International Publishing :  |b Imprint: Humana Press,  |c 2017. 
300 |a IX, 135 p. 18 illus., 17 illus. in color.  |b online resource. 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
347 |a text file  |b PDF  |2 rda 
490 1 |a Cancer Drug Discovery and Development,  |x 2196-9906 
505 0 |a 1.Introduction to Ex Vivo Cancer Models -- 2.Patient-derived Xenografts in Oncology -- 3.Organoid Culture: Applications in Development and Cancer -- 4. Microfluidics and future of cancer diagnostics -- 5.Advancing techniques and insights in circulating tumor cell (CTC) research -- 6.The Cancer Secretome -- 7.An overview of the tumor microenvironments and future of cancer therapy. . 
520 |a This volume will outline how to recreate the tumor microenvironment, to culture primary tumors without the need for developmental priming factors, and to deliver targeted therapeutics in a manner that recapitulates pharmacokinetics in vivo. Much of what may be learned from this volume will aid in understanding many aspects of the enhanced study of tumor cell biology in a physiologic context, open new avenues for drug screening and biomarker development, and accelerate the preclinical evaluation of novel personalized medicine strategies for patients in real time. 
650 0 |a Medicine. 
650 0 |a Cancer research. 
650 1 4 |a Biomedicine. 
650 2 4 |a Cancer Research. 
700 1 |a Aref, Amir R.  |e editor. 
700 1 |a Barbie, David.  |e editor. 
710 2 |a SpringerLink (Online service) 
773 0 |t Springer eBooks 
776 0 8 |i Printed edition:  |z 9783319453958 
830 0 |a Cancer Drug Discovery and Development,  |x 2196-9906 
856 4 0 |u http://dx.doi.org/10.1007/978-3-319-45397-2  |z Full Text via HEAL-Link 
912 |a ZDB-2-SME 
950 |a Medicine (Springer-11650)