Ex Vivo Engineering of the Tumor Microenvironment

• Corporate Author: SpringerLink (Online service)
• Other Authors: Aref, Amir R. (Editor), Barbie, David (Editor)
• Format: Electronic eBook
• Language: English
• Published: Cham : Springer International Publishing : Imprint: Humana Press, 2017.
• Series: Cancer Drug Discovery and Development,
• Subjects: Medicine.; Cancer research.; Biomedicine.; Cancer Research.

This volume will outline how to recreate the tumor microenvironment, to culture primary tumors without the need for developmental priming factors, and to deliver targeted therapeutics in a manner that recapitulates pharmacokinetics in vivo. Much of what may be learned from this volume will aid in un...

Table of Contents:

• 1.Introduction to Ex Vivo Cancer Models
• 2.Patient-derived Xenografts in Oncology
• 3.Organoid Culture: Applications in Development and Cancer
• 4. Microfluidics and future of cancer diagnostics
• 5.Advancing techniques and insights in circulating tumor cell (CTC) research
• 6.The Cancer Secretome
• 7.An overview of the tumor microenvironments and future of cancer therapy. .