The Blood Brain Barrier and Inflammation

• Corporate Author: SpringerLink (Online service)
• Other Authors: Lyck, Ruth (Editor), Enzmann, Gaby (Editor)
• Format: Electronic eBook
• Language: English
• Published: Cham : Springer International Publishing : Imprint: Springer, 2017.
• Series: Progress in Inflammation Research
• Subjects: Medicine.; Immunology.; Neurosciences.; Infectious diseases.; Cytokines.; Growth factors.; Cell membranes.; Biomedicine.; Membrane Biology.; Infectious Diseases.; Cytokines and Growth Factors.

Within the central nervous system (CNS) the constantly changing blood stream is separated from the CNS parenchyma by the blood brain barrier (BBB) restricting passage to selected immune cells. Under pathological conditions, however, viruses, bacteria, parasites and autoaggressive immune cells can pe...

Table of Contents:

• General Introduction to Barrier Mechanisms in the Central Nervous System
• Topological Aspects of the Blood-brain and Blood cerebrospinal Fluid Barriers and their Relevance in Inflammation Research
• The Contribution of the Extracellular Matrix to the BBB in Steady State and Inflammatory Conditions
• Pathophysiology of the Bloodbrain Barrier in Neuroinflammatory Diseases
• Leakage at Blood-neural Barriers
• Blood-Brain Barrier Transporters and Neuroinflammation: Partners in Neuroprotection and in Pathology
• MicroRNAs in Brain Endothelium and Inflammation
• Blood-Brain Barrier Dysfunction during Central Nervous System Autoimmune Diseases
• Pathways Across the Blood Brain Barrier
• Neuroinflammation in Bacterial Meningitis
• Blood Vessels in the Brain: a Signaling Hub in Brain Tumor Inflammation.