Resistance to Tyrosine Kinase Inhibitors

• Corporate Author: SpringerLink (Online service)
• Other Authors: Focosi, Daniele (Editor)
• Format: Electronic eBook
• Language: English
• Published: Cham : Springer International Publishing : Imprint: Springer, 2016.
• Series: Resistance to Targeted Anti-Cancer Therapeutics,
• Subjects: Medicine.; Cancer research.; Biomedicine.; Cancer Research.

The volume will serve as a primer on tyrosine kinase signaling and its importance in cancer. The volume will first introduce the common denominators of small-molecule and antibody-derived inhibitors, as well as the general phenomenon of resistance. The volume will then detail resistance to the most...

Table of Contents:

• Tyrosine Kinase Signaling Pathways in Normal and Cancer Cells
• Resistance to Tyrosine Kinase Inhibitors in different types of solid cancer
• The Resistance to Tyrosine Kinase Inhibitors in Chronic Myeloid Leukemia: An Overview
• Resistance to FLT3 Inhibitors
• Resistance to ALK inhibitors
• Resistance to Angiokinase Inhibitors
• Indications for Tyrosine Kinase Inhibitors in the Treatment of Solid Tumors.