Structural Bioinformatics Tools for Drug Design Extraction of Biologically Relevant Information from Structural Databases /

• Κύριοι συγγραφείς: Koča, Jaroslav (Συγγραφέας), Svobodová Vařeková, Radka (Συγγραφέας), Pravda, Lukáš (Συγγραφέας), Berka, Karel (Συγγραφέας), Geidl, Stanislav (Συγγραφέας), Sehnal, David (Συγγραφέας), Otyepka, Michal (Συγγραφέας)
• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Cham : Springer International Publishing : Imprint: Springer, 2016.
• Σειρά: SpringerBriefs in Biochemistry and Molecular Biology,
• Θέματα: Medicine.; Biomedical engineering.; Bioinformatics.; Biomedicine.; Biomedical Engineering/Biotechnology.; Computational Biology/Bioinformatics.

A large amount of structural data on biomacromolecules is available and the number of resolved structures is growing rapidly. This implies that we have an increasing opportunity to perform so far unprecedented analyses to obtain crucial biological insight. Biomacromolecular structural fragments such...

Πίνακας περιεχομένων:

• 1. Introduction
• 2. Biomacromolecular fragments
• 3. Databases
• 4. Detection & Extraction
• a. Biomacromolecular fragments and structural patterns
• b. channels and pores
• 5. Validation
• 6. Characterization
• a. Partial atomic charges
• b. Channel characteristics
• 7. Selected Examples.