The CAPRISA Clinical Trials: HIV Treatment and Prevention

• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Άλλοι συγγραφείς: Abdool Karim, Quarraisha (Επιμελητής έκδοσης), Abdool Karim, Salim S. (Επιμελητής έκδοσης), Baxter, Cheryl (Επιμελητής έκδοσης)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Cham : Springer International Publishing : Imprint: Springer, 2017.
• Θέματα: Medicine.; Health promotion.; Health informatics.; Infectious diseases.; Medicine & Public Health.; Health Promotion and Disease Prevention.; Infectious Diseases.; Health Informatics.

Since its inception 14 years ago, CAPRISA has conducted numerous clinical studies that have influenced international TB-HIV treatment guidelines as well as HIV prevention through innovations in the microbicide and vaccine fields. This book provides a historical account of how each of CAPRISA’s high...

Πίνακας περιεχομένων:

• Part I. Introduction
• Studies Linked to the Evolving HIV Epidemic in South Africa: Informing the CAPRISA Scientific Agenda
• CAPRISA: Establishing A Research Center to Undertake HIV Clinical Trials
• Overview of Clinical Trials
• Part II. CAPRISA Clinical Trials for HIV and HSV-2 Prevention
• Antiretrovirals for HIV Prevention
• Rolling out of tenofovir gel in family planning clinics: the CAPRISA 008 implementation trial
• Conditional cash transfers to reduce HIV risk in young women: the CAPRISA 007 cluster randomised control trial
• HIV vaccine and passive immunity trials
• Part III: CAPRISA Clinical Trials for HIV–TB Treatment
• CAPRISA 003: Timing of antiretroviral initiation in HIV-TB co-infected patients - The SAPiT Trial
• Scaling up TB-HIV integration in public health clinics: translating research findings into practice
• Part IV: Experiences and lessons learnt from clinical trials in CAPRISA
• Lessons from the Acute Infection Study: from Bench to Bedside
• Understanding sexual HIV transmission in women by focusing on the genital mucosa
• Part V: Essential support activities for the conduct of clinical trials
• Good practices in conducting clinical trials: Good Participatory Practice, Good Pharmacy Practice and Good Laboratory Practice
• Grants Management
• Taking science to the people: communication and media strategies for clinical trials
• Looking ahead: What Does the Future Hold for CAPRISA?
• Appendix
• Index. .