Metabolomics: From Fundamentals to Clinical Applications

• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Άλλοι συγγραφείς: Sussulini, Alessandra (Επιμελητής έκδοσης)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Cham : Springer International Publishing : Imprint: Springer, 2017.
• Σειρά: Advances in Experimental Medicine and Biology, 965
• Θέματα: Life sciences.; Gene therapy.; Medical genetics.; Metabolism.; Life Sciences.; Metabolomics.; Gene Therapy.; Gene Function.

This book provides a comprehensive view of metabolomics, from the basic concepts, through sample preparation and analytical methodologies, to data interpretation and applications in medicine. It is the first volume to cover metabolomics clinical applications while also emphasizing analytical and sta...

Πίνακας περιεχομένων:

• Part I: Fundamentals and analytical methodologies in metabolomics
• 1. Metabolomics: definitions and significance in systems biology
• 2. Collection and preparation of clinical samples for metabolomics
• 3. NMR strategies in metabolomics
• 5. Strategies involving MS combined with chromatography in metabolomics
• 6.MS combined with capillary electrophoresis in metabolomics
• Part II: Statistical analysis and data interpretation
• 7. Data pretreatment: How to prepare a metabolomics dataset for statistical analysis?
• 8. Chemometrics in metabolomics
• Understanding metabolomics data: Metabolite identification and biological relevance
• Part III: Applications and future trends of metabolomics in clinical cases
• 9. Applications of metabolomics in cancer studies
• 10. Chronic diseases and lifestyle biomarkers identification by metabolomics
• 11. Metabolomics in neurological and psychiatric diseases
• 12. Metabolite profiling by MS imaging
• 13. Single cell metabolomics .